Endotype-driven precision medicine in chronic rhinosinusitis
@article{Lou2019EndotypedrivenPM, title={Endotype-driven precision medicine in chronic rhinosinusitis}, author={H. Lou and C. Wang and L. Zhang}, journal={Expert Review of Clinical Immunology}, year={2019}, volume={15}, pages={1171 - 1183} }
ABSTRACT Introduction: Chronic rhinosinusitis (CRS) is a heterogeneous disease spectrum with variable phenotypes and endotypes that are not well characterized. Conventional treatment options are insufficient; recent research in precision medicine focuses on providing endotype-driven care based on underlying mechanisms. Areas covered: A comprehensive overview of CRS phenotypes and endotypes is provided. Biomarkers have been identified to predict prognosis and guide personalized pharmacotherapy… CONTINUE READING
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