Endotoxins: relationship between structure, function, and activity.

  title={Endotoxins: relationship between structure, function, and activity.},
  author={Klaus Brandenburg and Andra Beate Schromm and Thomas Gutsmann},
  journal={Sub-cellular biochemistry},
Endotoxins as amphiphilic components of the outer layer of the outer membrane of Gram-negative bacteria exert their immunostimulatory activity after release from bacterial cells. Thus, the characterization of the physicochemical properties of this glycolipid in physiological fluids is of utmost importance for an understanding of cell activation processes. Here, the essential physicochemical parameters describing endotoxins such as critical micellar concentration, acyl chain fluidity… CONTINUE READING
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