Endotoxin-neutralizing antimicrobial proteins of the human placenta.

  title={Endotoxin-neutralizing antimicrobial proteins of the human placenta.},
  author={Hun Sik Kim and Ju Cho and H. W. Park and Ho Joong Yoon and Mi Sun Kim and Sun Hee Kim},
  journal={Journal of immunology},
  volume={168 5},
Microbial colonization and infection of placental tissues often lead to adverse pregnancy outcomes such as preterm birth, a leading cause of neonatal morbidity and mortality. The fetal membranes of the placenta, a physical and active barrier to microbial invasion, encapsulate the fetus and secure its intrauterine environment. To examine the innate defense system of the human placenta, antimicrobial peptides were isolated from the fetal membranes of human placenta and characterized biochemically… CONTINUE READING


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