Endotoxin-induced effects on platelets and monocytes in an in vivo model of inflammation

@article{Klsch2007EndotoxininducedEO,
  title={Endotoxin-induced effects on platelets and monocytes in an in vivo model of inflammation},
  author={Thorsten K{\"a}lsch and Elif Elmas and Xuan Duc Nguyen and Nenad Suvajac and Harald Kl{\"u}ter and Martin Borggrefe and C.-E. Dempfle},
  journal={Basic Research in Cardiology},
  year={2007},
  volume={102},
  pages={460-466}
}
Chronic inflammation is a major contributing factor to atherosclerosis and various markers of inflammation, fibrinolysis and coagulation are upregulated in patients with established atherosclerotic disease. The aim of this study was to investigate the direct and short-term effects of inflammation on platelet and monocyte activation with an in vivo model of endotoxemia in healthy volunteers. In this study, 13 healthy male subjects with a mean age of 29.5±5.4 years received intravenous… CONTINUE READING