Endotoxin-free biologically active component of Escherichia coli.


The proteinaceous component of gram-negative bacteria, which has been termed "protodyne," enhances nonspecific host resistance while eliciting a slight pyrogenic response equivalent to 0.2% that of a typical endotoxin. Since this material still contains small amounts of carbohydrate and lipid, it was imperative to establish that its biological activities… (More)


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@article{Rosselet1969EndotoxinfreeBA, title={Endotoxin-free biologically active component of Escherichia coli.}, author={J P Rosselet and Samuel G. Murphy and Rachel Adamski and Murray J. Fletcher and Brian J Ludwig}, journal={Journal of bacteriology}, year={1969}, volume={98 2}, pages={434-6} }