Endotoxin activity level and septic shock: a possible role for specific anti-endotoxin therapy?

@article{Monti2010EndotoxinAL,
  title={Endotoxin activity level and septic shock: a possible role for specific anti-endotoxin therapy?},
  author={Gianpaola Monti and Maurizio A. Bottiroli and Giacinto Pizzilli and Maria Minnini and Valeria Terzi and Irene Vecchi and Giovanni Gesu and Paolo Riccardo Brioschi and Sergio Vesconi and Giampaolo Casella},
  journal={Contributions to nephrology},
  year={2010},
  volume={167},
  pages={102-10}
}
Endotoxin activity (EA) plays an essential role in sepsis syndrome pathogenesis. There has been considerable interest in measuring and removing EA to predict and improve the morbidity and mortality of patients with sepsis. We performed a prospective study to assess the prevalence of EA in critically ill patients and its association with organ dysfunction and outcome, as well as in septic shock. EA (EAA(TM)) was measured within 24 h from onset of refractory septic shock in an intensive care unit… CONTINUE READING