Endotoxemia in obstructive jaundice. Observations on cause and clinical significance.

  title={Endotoxemia in obstructive jaundice. Observations on cause and clinical significance.},
  author={James N Thompson and J M Cohen and Richard H. Moore and J. Ian Blenkharn and J. Stanley McConnell and J A Matkin and Leslie Harold Blumgart},
  journal={American journal of surgery},
  volume={155 2},
Perioperative endotoxemia was detected in 24 of 40 patients who underwent operation for obstructive jaundice (bilirubin level greater than 5.8 mg/dl). Endotoxemia was associated with an increased admission serum bilirubin level (p less than 0.05) and white blood cell count (p less than 0.05) and a decreased hematocrit value (p less than 0.05), but there was no significant association with other established preoperative risk factors. Patients with preoperative endotoxemia had a decreased… CONTINUE READING


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