Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats.

@article{Huang2012EndotoxemiaEK,
  title={Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats.},
  author={Li-Tung Huang and Jia-Fu Hung and Chih-Cheng Chen and Chih-Sung Hsieh and Hong-Ren Yu and Chien-Ning Hsu and You-Lin Tain},
  journal={Shock},
  year={2012},
  volume={37 4},
  pages={441-8}
}
Cirrhosis increases the risk of kidney injury and sepsis, leading to increased mortality. Elevated levels of plasma asymmetric dimethylarginine (ADMA) occur in patients critically ill with cirrhosis, renal failure, and sepsis. We used a rat model of cirrhosis with superimposed sepsis to assess the relationship of plasma and tissue ADMA profiles with acute… CONTINUE READING