Endothelium modulates anion channel-dependent aortic contractions to iodide.

Abstract

Anion currents contribute to vascular smooth muscle (VSM) membrane potential. The substitution of extracellular chloride (Cl) with iodide (I) or bromide (Br) initially inhibited and then potentiated isometric contractile responses of rat aortic rings to norepinephrine. Anion substitution alone produced a small relaxation, which occurred despite a lack of… (More)

8 Figures and Tables

Topics

  • Presentations referencing similar topics