Endothelium in Diseased States

  title={Endothelium in Diseased States},
  author={I. Bern{\'a}tov{\'a} and R. Andriantsitohaina and S. Arribas and V. Matchkov},
  journal={BioMed Research International},
Endothelium is the endocrine organ essential for maintenance of homeostasis in the entire body. Endothelium operates by a broad spectrum of signaling molecules controlling the contractile state of vascular smooth muscles and cardiomyocytes; long distance intercellular synchronization within the vascular wall; adhesive, coagulant, and rheological properties of blood; and permeability of the vascular wall. Dysfunctions in these signaling pathways result in loss of the important homeostatic… Expand
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