Endothelium-derived nitric oxide contributes to the regulation of venous tone in humans.

BACKGROUND Although nitric oxide (NO) is known to play an important part in the regulation of arterial tone, little is known about its role in veins. The aim of this study was to investigate the role of basal and stimulated NO activity in the regulation of tone of the human venous capacitance bed. METHODS AND RESULTS We measured venous tone using… CONTINUE READING