Endothelium-dependent relaxation of small resistance vessels is impaired in patients with autosomal dominant polycystic kidney disease.

@article{Wang2000EndotheliumdependentRO,
  title={Endothelium-dependent relaxation of small resistance vessels is impaired in patients with autosomal dominant polycystic kidney disease.},
  author={Dan Wang and Jens Iversen and Svend Strandgaard},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2000},
  volume={11 8},
  pages={1371-6}
}
Impaired endothelium-dependent relaxation has been demonstrated previously in resistance vessels of Han:SPRD polycystic kidney disease rats. The aim of the present study was to investigate whether endothelium-dependent relaxation is reduced also in patients with autosomal dominant polycystic kidney disease (ADPKD) and whether this is influenced by the nitric oxide (NO) system. Small subcutaneous resistance vessels from normotensive ADPKD patients with normal or near-normal renal function (n = 9… CONTINUE READING

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