Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries.

Abstract

Recent studies have identified that the novel membrane estrogen receptor, G protein-coupled receptor 30 (GPR30), is present in blood vessels. However, the signaling mechanisms associated with GPR30 in the vasculature remain unclear. We examined whether putative agonists of GPR30 exert vasorelaxant and/or antioxidant effects similar to those reported for… (More)
DOI: 10.1152/ajpheart.00878.2009

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