Endothelium-dependent higenamine-induced aortic relaxation in isolated rat aorta.

@article{Wong1997EndotheliumdependentHA,
  title={Endothelium-dependent higenamine-induced aortic relaxation in isolated rat aorta.},
  author={K. K. Wong and C F Lo and C. M. Chen},
  journal={Planta medica},
  year={1997},
  volume={63 2},
  pages={
          130-2
        }
}
The pharmacological action of higenamine in isolated rat aorta was investigated. Although the beta-adrenoceptor antagonist propranolol (1 x 10(-5) M) completely blocked the beta-adrenoceptor agonist higenamine in inducing a positive chronotropic activity in isolated mouse atria, the higenamine-induced aortic relaxation was not completely antagonized by this concentration of propranolol. The present data also demonstrate that the higenamine-induced aortic relaxation was attenuated in the absence… 
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