Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries.

@article{Hull1986EndotheliumdependentFD,
  title={Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries.},
  author={Stephen S. Hull and Lana Kaiser and Mark D. Jaffe and Harvey V. Sparks},
  journal={Blood vessels},
  year={1986},
  volume={23 4-5},
  pages={183-98}
}
We have characterized the dilation response to increased blood flow in the canine femoral and saphenous arteries. An arterio-venous shunt was created and changes in arterial diameter measured by sonomicrometer crystals. Increasing shunt flow approximately 10-fold caused a 9% increase in femoral and 15% increase in saphenous artery diameter. The dilation response consisted of a transient decrease in diameter, followed by a rapid dilation and a slow return to control when flow was decreased. The… CONTINUE READING

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