Endothelium-dependent and independent vasorelaxation induced by an n-butanolic fraction of bark of Scutia buxifolia Reiss (Rhamanaceae).

@article{Silva2012EndotheliumdependentAI,
  title={Endothelium-dependent and independent vasorelaxation induced by an n-butanolic fraction of bark of Scutia buxifolia Reiss (Rhamanaceae).},
  author={Rita de C{\'a}ssia Melo Vilhena de Andrade Fonseca da Silva and Sandra Crestani and Priscila de Souza and Aline Augusti Boligon and Margareth Linde Athayde and Adair Roberto Soares dos Santos and Maria Consuelo Andrade Marques and C{\^a}ndida Aparecida Leite Kassuya and Jos{\'e} Eduardo da Silva-Santos},
  journal={Journal of ethnopharmacology},
  year={2012},
  volume={141 3},
  pages={997-1004}
}
ETHNOPHARMACOLOGICAL RELEVANCE Scutia buxifolia has been widely used in Brazilian folk medicine as an anti-hypertensive agent. We evaluated the vascular effects and mechanism involved in the relaxation of aorta induced by an n-butanolic fraction (BuOH) from Scutia buxifolia. MATERIALS AND METHODS Rat aortic rings precontracted by phenylephrine (1 μM) were… CONTINUE READING