Endothelium-dependent and independent effects of garlic on rat aorta.

  title={Endothelium-dependent and independent effects of garlic on rat aorta.},
  author={Yusuf Ozt{\"u}rk and S{\"u}leyman Aydin and M{\"u}berra Koşar and Kemal H{\"u}sn{\"u} Can Başer},
  journal={Journal of ethnopharmacology},
  volume={44 2},
Effects of garlic on isolated rat aorta were investigated by comparing with those of acetylcholine and L-arginine in the presence and absence of endothelium. For this purpose, certain linear and non-linear regression models were applied for concentration-response curves obtained by acetylcholine, L-arginine and garlic in the rat aorta. Garlic caused dose-dependent relaxations in isolated rat aorta which were attenuated by the removal of endothelium as in the case of acetylcholine. However, the… CONTINUE READING