Endothelium—role in regulation of coagulation and inflammation

@inproceedings{Hinsbergh2011EndotheliumroleIR,
  title={Endothelium—role in regulation of coagulation and inflammation},
  author={Victor W. M. van Hinsbergh},
  booktitle={Seminars in Immunopathology},
  year={2011}
}
By its strategic position at the interface between blood and tissues, endothelial cells control blood fluidity and continued tissue perfusion while simultaneously they direct inflammatory cells to areas in need of defense or repair. The endothelial response depends on specific tissue needs and adapts to local stresses. Endothelial cells counteract coagulation by providing tissue factor and thrombin inhibitors and receptors for protein C activation. The receptor PAR-1 is differentially activated… CONTINUE READING

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Platelets can also facilitate leukocyte - endothelium interaction .
Platelets can also facilitate leukocyte - endothelium interaction .
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