Endothelium, aging, and hypertension.

  title={Endothelium, aging, and hypertension.},
  author={Stefano Taddei and Agostino Virdis and Lorenzo Ghiadoni and Daniele Versari and Antonio Salvetti},
  journal={Current hypertension reports},
  volume={8 1},
Endothelium plays a primary role in modulating vascular tone and structure through production of the relaxing factor nitric oxide (NO), which also protects the vessel wall against the pathogenesis of atherosclerosis and thrombosis. A dysfunctioning endothelium due to reduced NO availability and increased production of oxidative stress is considered an early indicator of atherothrombotic damage and of cardiovascular events. Aging is associated with the development of cardiovascular structural… CONTINUE READING


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