Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation.

@article{Asai2010EndothelinRT,
  title={Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation.},
  author={Rieko Asai and Yukiko Kurihara and Kou Fujisawa and Takahiro Sato and Yumiko Kawamura and Hiroki Kokubo and Kazuo Tonami and Koichi Nishiyama and Yasunobu Uchijima and Sachiko Miyagawa-Tomita and Hiroki Kurihara},
  journal={Development},
  year={2010},
  volume={137 22},
  pages={3823-33}
}
The avian and mammalian heart originates from two distinct embryonic regions: an early differentiating first heart field and a dorsomedially located second heart field. It remains largely unknown when and how these subdivisions of the heart field divide into regions with different fates. Here, we identify in the mouse a subpopulation of the first (crescent-forming) field marked by endothelin receptor type A (Ednra) gene expression, which contributes to chamber myocardium through a unique type… CONTINUE READING

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