Endothelin converting enzyme (ECE) activity in normal pregnancy and preeclampsia.

  title={Endothelin converting enzyme (ECE) activity in normal pregnancy and preeclampsia.},
  author={Gunilla Ajne and Kerstin Wolff and Frej Y Fyhrquist and Kjell A M Carlstr{\"o}m and Anette Hems{\'e}n-M{\"o}rtberg and Henry Nisell},
  journal={Hypertension in pregnancy},
  volume={22 3},
OBJECTIVE Enhanced production of endothelin-1, due to endothelial cell dysfunction has been considered to be the cause of increased plasma levels of endothelin-1 in preeclampsia. The present study was aimed at analyzing endothelin-converting-enzyme activity, (which reflect the production rate of endothelin-1 (ET-1) from big endothelin-1 (big ET-1)), big endothelin-1, and endothelin-1 concentrations from women with preeclampsia compared to normal pregnant women. Moreover, we analyzed plasma… CONTINUE READING


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