Endothelin attenuates endothelium-dependent platelet inhibition in man.

Abstract

AIM The vascular endothelium produces several substances, including nitric oxide (NO) and endothelin-1 (ET-1), which participate in the regulation of vascular tone in humans. Both these substances may exert other actions of importance for cardiovascular disease, e.g. effects on vascular smooth muscle cell proliferation and inflammation, and NO inhibits… (More)
DOI: 10.1111/j.1748-1716.2009.02062.x

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