Endothelin-1 modulates methacholine-induced cutaneous vasodilatation but not sweating in young human skin.

@article{Halili2016Endothelin1MM,
  title={Endothelin-1 modulates methacholine-induced cutaneous vasodilatation but not sweating in young human skin.},
  author={Lyra Halili and Maya Sarah Singh and Naoto Fujii and Lacy M. Alexander and Glen P. Kenny},
  journal={The Journal of physiology},
  year={2016},
  volume={594 12},
  pages={3439-52}
}
KEY POINTS Endothelin-1 (ET-1) is a potent endothelial-derived vasoconstrictor that may modulate cholinergic cutaneous vascular regulation. Endothelin receptors are also expressed on the human eccrine sweat gland, although it remains unclear whether ET-1 modulates cholinergic sweating. We investigated whether ET-1 attenuates cholinergic cutaneous… CONTINUE READING