Endothelin-1 and acute myocardial infarction: a no-reflow mediator after successful percutaneous myocardial revascularization.

@article{Niccoli2006Endothelin1AA,
  title={Endothelin-1 and acute myocardial infarction: a no-reflow mediator after successful percutaneous myocardial revascularization.},
  author={Giampaolo Niccoli and Gaetano Antonio Lanza and Sidney Shaw and Enrico Romagnoli and Domenico Gioia and Francesco Burzotta and Carlo Trani and Mario Attilio Mazzari and Rocco Mongiardo and Maria De Vita and Antonio Giuseppe Rebuzzi and Thomas Felix L{\"u}scher and Filippo Crea},
  journal={European heart journal},
  year={2006},
  volume={27 15},
  pages={1793-8}
}
AIMS No-reflow after a primary percutaneous coronary intervention (PCI) is associated with a high incidence of left ventricular (LV) failure and a poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and an important modulator of neutrophil function. Elevated systemic ET-1 levels have recently been reported to predict a poor prognosis in patients with acute myocardial infarction (AMI) treated by primary PCI. We aimed to investigate the relationship between… CONTINUE READING