Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.

Abstract

Primary myelofibrosis is characterized by the development of fibrosis in the bone marrow that contributes to ineffective hematopoiesis. Bone marrow fibrosis is the result of a complex and not yet fully understood interaction among megakaryocytes, myeloid cells, fibroblasts, and endothelial cells. Here, we report that >30% of the endothelial cells in the… (More)
DOI: 10.1016/j.ajpath.2017.04.006

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Cite this paper

@article{Erba2017EndothelialtoMesenchymalTI, title={Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.}, author={Benedetta Gaia Erba and Cristian Gruppi and Monica Corada and Federica Pisati and Vittorio Rosti and Niccolo' Bartalucci and J. Villeval and Alessandro Maria Vannucchi and Giovanni Barosi and Alessandra Balduini and Elisabetta Dejana}, journal={The American journal of pathology}, year={2017}, volume={187 8}, pages={1879-1892} }