Endothelial-rich microenvironment supports growth and branching morphogenesis of prostate epithelial cells.


BACKGROUND Development of epithelial organs depends on interaction between the epithelium and the underlying mesenchyme including the vasculature. The aim of this study was to explore the morphogenic effect of endothelial cells on prostate epithelial cell lines in 3D culture and to establish an in vitro model for prostate branching morphogenesis. METHODS… (More)
DOI: 10.1002/pros.22634


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