Endothelial regulation of coronary microcirculation in health and cardiometabolic diseases.

@article{Koller2013EndothelialRO,
  title={Endothelial regulation of coronary microcirculation in health and cardiometabolic diseases.},
  author={A. E. Koller and M{\'a}rta Balask{\'o} and Zsolt Bagi},
  journal={Internal and emergency medicine},
  year={2013},
  volume={8 Suppl 1},
  pages={
          S51-4
        }
}
Cardiometabolic disorders have been shown to impair coronary microvascular functions leading to diminished cardiac performance and increased mortality. In this review, we focus on the molecular pathomechanisms of impaired endothelium-dependent and flow-induced dysregulation of coronary vasomotor tone in cardiometabolic disorders such as obesity, diabetes mellitus or hyperhomocysteinemia based on animal experiments and human studies. We also briefly summarize the relationship among key signaling… CONTINUE READING

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