Endothelial progenitor cells in pulmonary hypertension - dawn of cell-based therapy?

  title={Endothelial progenitor cells in pulmonary hypertension - dawn of cell-based therapy?},
  author={Mark R Toshner and Nicholas W Morrell},
  journal={International journal of clinical practice. Supplement},
There is mounting interest in the concept of endothelial progenitor cell (EPC) therapy for the treatment of pulmonary arterial hypertension (PAH). Recent successful pilot studies in idiopathic PAH have raised questions about the contribution of progenitor cells circulating in the peripheral blood to pulmonary vascular homeostasis and to the process of vascular remodelling. This review will summarise the work performed to date in animal and human therapeutic trials and clarify what is known… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 37 references

Cellular and molecular basis of pulmonary arterial hypertension

  • CD Cool, JS Stewart, P Werahera
  • J Am Coll Cardiol
  • 2009

Bone marrow-derived

  • T Ziegelhoeffer, B Fernandez, S Kostin
  • 2008

Similar Papers

Loading similar papers…