Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis.

@article{Simper2003EndothelialPC,
  title={Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis.},
  author={D. Simper and Shaohua Wang and Arjun Deb and David Holmes and Christopher G A McGregor and Robert R Frantz and Sudhir Shyam Kushwaha and Noel M. Caplice},
  journal={Circulation},
  year={2003},
  volume={108 2},
  pages={143-9}
}
BACKGROUND Recent studies in animals suggest that circulating recipient endothelial precursors may participate in the biology of transplant vasculopathy. It is currently unknown whether a similar interaction between recipient endothelial cells and the vessel wall occurs in human subjects undergoing allogeneic cardiac transplantation. METHODS AND RESULTS Circulating endothelial cells and endothelial progenitor cells (EPCs) were quantified in 15 cardiac transplantation subjects with and without… CONTINUE READING