Endothelial progenitor cells: therapeutic perspective for ischemic stroke.

@article{Zhao2013EndothelialPC,
  title={Endothelial progenitor cells: therapeutic perspective for ischemic stroke.},
  author={Yan-ping Zhao and Bin Yuan and Ji Chen and De-Hui Feng and Bin Zhao and Chao Qin and Yan-fang Chen},
  journal={CNS neuroscience & therapeutics},
  year={2013},
  volume={19 2},
  pages={67-75}
}
Endothelial progenitor cells (EPCs), which can be cultured in vitro from mononuclear cells in peripheral blood or bone marrow, express both hematopoietic stem cell and endothelial cell markers on their surface. They are believed to participate in endothelial repair and postnatal angiogenesis due to their abilities of differentiating into endothelial cells and secreting protective cytokines and growth factors. Mounting evidence suggests that circulating EPCs are reduced and dysfunctional in… CONTINUE READING

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