Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLCbeta2 axis.

@article{Maeng2009EndothelialPC,
  title={Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLCbeta2 axis.},
  author={Yong-Sun Maeng and Hyun-Jung Choi and Ja-Young Kwon and Young Nyun Park and Kyu-Sil Choi and Jeong-Ki Min and Yun-Hee Kim and Pann-Ghill Suh and Kyung-Sun Kang and Moo-Ho Won and Young Myeong Kim and Young-Guen Kwon},
  journal={Blood},
  year={2009},
  volume={113 1},
  pages={
          233-43
        }
}
Homing of endothelial progenitor cells (EPCs) to the neovascular zone is now considered to be an essential step in the formation of vascular networks during embryonic development and also for neovascularization in postnatal life. We report here the prominent role of the insulin-like growth factor 2 (IGF2)/IGF2 receptor (IGF2R) system in promoting EPC homing. With high-level expression of IGF2R in EPCs, IGF2-induced hypoxic conditions stimulated multiple steps of EPC homing in vitro and promoted… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 48 CITATIONS

Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy

  • Journal of Hematology & Oncology
  • 2015
VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Helicobacter pylori-derived Heat shock protein 60 enhances angiogenesis via a CXCR2-mediated signaling pathway.

  • Biochemical and biophysical research communications
  • 2010
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Endothelial Ca2+ Signaling, Angiogenesis and Vasculogenesis: Just What It Takes to Make a Blood Vessel

Francesco Moccia, Sharon Negri, Mudhir Shekha, Pawan Faris, Germano Guerra
  • International journal of molecular sciences
  • 2019
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Biology and significance of signalling pathways activated by IGF-II.

  • Growth factors
  • 2012
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 51 REFERENCES