Endothelial progenitor cell function, apoptosis, and telomere length in overweight/obese humans.

@article{Maceneaney2010EndothelialPC,
  title={Endothelial progenitor cell function, apoptosis, and telomere length in overweight/obese humans.},
  author={Owen J Maceneaney and Erich James Kushner and Christian M. Westby and Jennifer Nell Cech and Jared J. Greiner and Brian L Stauffer and Christopher A DeSouza},
  journal={Obesity},
  year={2010},
  volume={18 9},
  pages={
          1677-82
        }
}
Excess adiposity is associated with increased cardiovascular morbidity and mortality. Endothelial progenitor cells (EPCs) play an important role in vascular repair. We tested the hypothesis that increased adiposity is associated with EPC dysfunction, characterized by diminished capacity to release angiogenic cytokines, increased apoptotic susceptibility, reduced cell migration, and shorter telomere length. A total of 67 middle-aged and older adults (42-67 years) were studied: 25 normal weight… CONTINUE READING
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