Endothelial nitric oxide synthase genetic variation and essential hypertension risk in Han Chinese: the Fangshan study

@article{Niu2009EndothelialNO,
  title={Endothelial nitric oxide synthase genetic variation and essential hypertension risk in Han Chinese: the Fangshan study},
  author={W Niu and Y Qi and L Zhang and Bin Wang and S-Q Hou and X-Y Zhai and C Qiu},
  journal={Journal of Human Hypertension},
  year={2009},
  volume={23},
  pages={136-139}
}
Of the candidate genes thought to be logical for an individual's hypertension susceptibility, endothelial nitric oxide (NO) synthase gene (protein: eNOS and gene: eNOS) ranks high. Evidence is mounting suggesting that enhanced production or bioavailability of the enzyme eNOS that synthesizes NO in endothelial cells may lead to the constitutive release of NO, which exerts vasoprotective effects in blood pressure (BP) regulation. 

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