Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes.

@article{Awata2004EndothelialNO,
  title={Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes.},
  author={Takuya Awata and Tamotsu Neda and Hiroyuki Iizuka and Susumu Kurihara and Tomoko Ohkubo and Nobuki Takata and Masataka Osaki and Masaki Watanabe and Youhei Nakashima and Takahiro Sawa and Kouichi Inukai and Ikuo Inoue and Masayuki Shibuya and Keisuke Mori and Shin Yoneya and Shigehiro Katayama},
  journal={Diabetes care},
  year={2004},
  volume={27 9},
  pages={2184-90}
}
OBJECTIVE We examined the endothelial nitric oxide (eNOS) gene polymorphisms to assess its possible association with diabetic retinopathy and macular edema. RESEARCH DESIGN AND METHODS A total of 226 patients with type 2 diabetes and 186 healthy subjects were studied. Type 2 diabetic patients consisted of 110 patients without retinopathy, 46 patients with nonproliferative diabetic retinopathy, and 71 patients with proliferative diabetic retinopathy. Diabetic macular edema was present in 48… CONTINUE READING
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