Endothelial nitric oxide synthase Glu298Asp, 4b/a, and T-786C polymorphisms in type 2 diabetic retinopathy.


OBJECTIVE The possible association between the endothelial nitric oxide (eNOS) gene T-786C (promoter region), 27-bp repeat 4b/4a (intron 4), and Glu298Asp (exon 7) polymorphisms with diabetic retinopathy (DR) was investigated. DESIGN A retrospective case-control study. PATIENTS A total of 872 type 2 diabetes (T2DM) patients were studied, of whom 383… (More)