Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs


A major determinant of the potential size of cell/scaffold constructs in tissue engineering is vascularization. The aims of this study were twofold: first to determine the in vitro angiogenic and osteogenic gene-expression profiles of endothelial cells (ECs) and mesenchymal stem cells (MSCs) cocultured in a dynamic 3D environment; and second, to assess… (More)
DOI: 10.1186/scrt202


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