Endothelial microparticles activate endothelial cells to facilitate the inflammatory response.

@article{Liu2017EndothelialMA,
  title={Endothelial microparticles activate endothelial cells to facilitate the inflammatory response.},
  author={Yiyun Liu and Ruyuan Zhang and Hongping Qu and Jun Wu and Lei Li and Y. C. Edwin Tang},
  journal={Molecular medicine reports},
  year={2017},
  volume={15 3},
  pages={1291-1296}
}
Endothelial microparticles (EMPs) and endothelial cells (ECs) are involved in the pathophysiological mechanisms of sepsis and septic shock. EMPs are small vesicles released by ECs and are considered biomarkers for endothelial cell function and mediators for intercellular information exchange. However, the effect of EMPs on their parental ECs remains unknown. The present study collected tumor necrosis factor‑α‑derived EMPs and detected the proinflammatory cytokines released from unstimulated and… CONTINUE READING

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