Endothelial mediators and communication through vascular gap junctions.

  title={Endothelial mediators and communication through vascular gap junctions.},
  author={Cor de Wit and Bernd Hoepfl and Stephanie E W{\"o}lfle},
  journal={Biological chemistry},
  volume={387 1},
Cellular interaction in vessels is achieved by multiple communication pathways, including gap junctions (GJs). They provide intercellular channels, allowing direct interaction of endothelial and smooth muscle cells and the coordination of cellular behaviour along the vessel. The latter is a prerequisite for large flow increases because an adaptation of resistance along the vessel length is required. Longitudinal communication is studied by confined local stimulation of arterioles and the… CONTINUE READING


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