Endothelial loss and regeneration in a model of transplant arteriosclerosis.

  title={Endothelial loss and regeneration in a model of transplant arteriosclerosis.},
  author={Hidenori Gohra and Thomas O. McDonald and Edward Donald Verrier and Salim ud din Aziz},
  volume={60 1},
Early endothelial injury may play a role in the development of transplant arteriosclerosis. The present study documents early endothelial changes using a rat aortic graft model. Abdominal aortic allografts from PVG rats were orthotopically transplanted to DA rats. Controls were DA to DA transplants. Endothelial cell (EC) injury, regeneration, and leukocyte infiltration in the intima were evaluated using scanning electron microscopy and histological and immunocytochemical techniques… CONTINUE READING
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