Endothelial lipase is increased in vivo by inflammation in humans.

@article{Badellino2008EndothelialLI,
  title={Endothelial lipase is increased in vivo by inflammation in humans.},
  author={Karen O. Badellino and Megan L. Wolfe and Muredach P. Reilly and Daniel J. Rader},
  journal={Circulation},
  year={2008},
  volume={117 5},
  pages={678-85}
}
BACKGROUND Endothelial lipase (EL) is a plasma lipase that we previously reported to be significantly correlated with all features of the metabolic syndrome in humans, including directly with measures of adiposity and inversely with high-density lipoprotein cholesterol levels. We hypothesized that inflammation associated with obesity results in upregulation of EL. We determined the relationship between inflammatory markers and EL levels in a cohort of healthy persons recruited on the basis of… CONTINUE READING
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Gender differences in the innate immune response and vascular reactivity following the administration of endotoxin to human volunteers

LT van Eijk, MJ Dorresteijn, +3 authors P. Pickkers
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