Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli.

@article{Mcdonald1994EndothelialGA,
  title={Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli.},
  author={Donald M. Mcdonald},
  journal={The American journal of physiology},
  year={1994},
  volume={266 1 Pt 1},
  pages={
          L61-83
        }
}
This study determined the number of endothelial gaps in venules of the rat trachea and related these values to the amount of plasma extravasation after an inflammatory stimulus (neurogenic inflammation). From 1 to 30 min after the stimulus, vessels were fixed by vascular perfusion, and endothelial cell borders were stained with silver nitrate, which made it possible to quantify the number and distribution of endothelial gaps. It also was possible to quantify the leukocyte attachment sites, to… CONTINUE READING
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