Endothelial function in health and disease: new insights into the genesis of cardiovascular disease.

@article{Quyyumi1998EndothelialFI,
  title={Endothelial function in health and disease: new insights into the genesis of cardiovascular disease.},
  author={Arshed A Quyyumi},
  journal={The American journal of medicine},
  year={1998},
  volume={105 1A},
  pages={32S-39S}
}
The vascular endothelium secretes factors that not only modulate blood vessel tone, but also participate in the development and progression of atherosclerosis through their effects on platelet adhesion and aggregation, thrombogenicity, and cell proliferation. Altered activities of these substances in patients with risk factors for cardiovascular disease (e.g., hypercholesterolemia, hypertension, diabetes, aging, postmenopausal status, smoking, and infections) appear to underlie the… CONTINUE READING
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