Endothelial function and cardiovascular events in chronic kidney disease.

  title={Endothelial function and cardiovascular events in chronic kidney disease.},
  author={Yoshihiro Hirata and Seigo Sugiyama and Eiichiro Yamamoto and Yasushi Matsuzawa and Eiichi Akiyama and Hiroaki Kusaka and Koichiro Fujisue and Hirofumi Kurokawa and Junichi Matsubara and Koichi Sugamura and Hirofumi Maeda and Satomi Iwashita and Hideaki Jinnouchi and Kunihiko Matsui and Hisao Ogawa},
  journal={International journal of cardiology},
  volume={173 3},
BACKGROUND As patients with chronic kidney disease (CKD) are at high risk of developing coronary artery disease (CAD), it is important to stratify their cardiovascular risk. We investigated whether peripheral endothelial dysfunction is associated with the presence of CAD in patients with CKD and is a predictor of cardiovascular events. METHODS We enrolled 383 CKD patients with at least one coronary risk factor. Peripheral endothelial function was assessed by reactive hyperemia peripheral… CONTINUE READING


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