Endothelial dysfunction in patients with severe acute pancreatitis: improved by continuous blood purification therapy.

@article{Chen2007EndothelialDI,
  title={Endothelial dysfunction in patients with severe acute pancreatitis: improved by continuous blood purification therapy.},
  author={Z Chen and Z Liu and Chang Yu and D Ji and L S-W Li},
  journal={The International journal of artificial organs},
  year={2007},
  volume={30 5},
  pages={393-400}
}
  • Z Chen, Z Liu, +2 authors L S-W Li
  • Published 2007 in The International journal of artificial organs
OBJECTIVES Endothelium dysfunction is one of the critical pathophysiologic disorders in patients with severe acute pancreatitis (SAP). To investigate the effect of continuous blood purification (CBP) on endothelial function, we conducted a prospective study of 20 patients with SAP, 9 of whom had evidence of sepsis. METHODS All patients underwent CVVH for 72 h. Soluble E-selectin (sE-selectin), soluble thrombomodulin, permeability of the endothelial monolayer, and endothelial intracellular… CONTINUE READING

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