Endothelial dysfunction in metabolic and vascular disorders.

  title={Endothelial dysfunction in metabolic and vascular disorders.},
  author={Marija M. Polovina and Tatjana S Potpara},
  journal={Postgraduate medicine},
  volume={126 2},
Vascular endothelium has important regulatory functions in the cardiovascular system and a pivotal role in the maintenance of vascular health and metabolic homeostasis. It has long been recognized that endothelial dysfunction participates in the pathogenesis of atherosclerosis from early, preclinical lesions to advanced, thrombotic complications. In addition, endothelial dysfunction has been recently implicated in the development of insulin resistance and type 2 diabetes mellitus (T2DM… CONTINUE READING


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