Endothelial dysfunction in dengue virus pathology.

  title={Endothelial dysfunction in dengue virus pathology.},
  author={Peter Vervaeke and Kurt Vermeire and Sandra Liekens},
  journal={Reviews in medical virology},
  volume={25 1},
Dengue virus (DENV) is a leading cause of illness and death, mainly in the (sub)tropics, where it causes dengue fever and/or the more serious diseases dengue hemorrhagic fever and dengue shock syndrome that are associated with changes in vascular permeability. Despite extensive research, the pathogenesis of DENV is still poorly understood and, although endothelial cells represent the primary fluid barrier of the blood vessels, the extent to which these cells contribute to DENV pathology is… CONTINUE READING
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