Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea.

@article{Priou2010EndothelialDA,
  title={Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea.},
  author={Pascaline Priou and Fr{\'e}d{\'e}ric Gagnadoux and Angela Tesse and Maria Letizia Mastronardi and Abdelali Agouni and Nicole Meslier and Jean-Louis Racineux and Maria Carmen Mart{\'i}nez and Wojciech Trzepizur and Ramaroson Andriantsitohaina},
  journal={The American journal of pathology},
  year={2010},
  volume={177 2},
  pages={
          974-83
        }
}
Endothelial dysfunction is involved in vascular complications of obstructive sleep apnea (OSA). In this study, circulating microparticles (MPs) from patients with OSA-induced nocturnal desaturations were characterized and their effects on endothelial function were evaluated. Two age-matched groups of patients undergoing polysomnography for OSA were compared: 35 desaturators with a 3% oxyhemoglobin desaturation index (ODI) > or = 10 events per hour of sleep and 27 nondesaturators with ODI <10… CONTINUE READING
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