Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: cause or association?

@article{Moody2012EndothelialDA,
  title={Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: cause or association?},
  author={William Moody and Nicola Catherine Edwards and Melanie Madhani and Colin Dominic Chue and Richard Paul Steeds and Charles Ferro and Jonathan Nicholas Townend},
  journal={Atherosclerosis},
  year={2012},
  volume={223 1},
  pages={86-94}
}
Chronic kidney disease (CKD) is strongly associated with cardiovascular disease (CVD); a graded inverse relationship between estimated glomerular filtration rate (eGFR) and cardiovascular event rates has emerged from large-scale observational studies. Chronic kidney disease is also associated with endothelial dysfunction (ED) although the precise relationship with GFR and the "threshold" at which ED begins are contentious. Abnormal endothelial function is certainly present in late-stage CKD but… CONTINUE READING

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