Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia.

@article{Weiss2002EndothelialDA,
  title={Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia.},
  author={Norbert Weiss and Christiane Keller and Ulrich Hoffmann and Joseph Loscalzo},
  journal={Vascular medicine},
  year={2002},
  volume={7 3},
  pages={227-39}
}
Mildly elevated plasma homocysteine levels are an independent risk factor for atherothrombotic vascular disease in the coronary, cerebrovascular, and peripheral arterial circulation. Endothelial dysfunction as manifested by impaired endothelium-dependent regulation of vascular tone and blood flow, by increased recruitment and adhesion of circulating inflammatory cells to the endothelium, and by a loss of endothelial cell antithrombotic function contributes to the vascular disorders linked to… CONTINUE READING

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