Endothelial dysfunction: Possible mechanisms and ways of correction.


BACKGROUND Endothelial function is impaired in atherosclerosis, hypertension, diabetes and aging, and this may be associated with an attenuated ability of endothelial cells to generate nitric oxide (NO). OBJECTIVES To evaluate possible alterations in endothelium-dependent relaxation in rat aortic rings, the activity of constitutive NO synthase and… (More)


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